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J Gen Virol 1 (1967), 471-478; DOI 10.1099/0022-1317-1-4-471
© 1967 Society for General Microbiology

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The Role of Arginine in the Replication of Herpes Simplex Virus

Y. Becker, U. Olshevsky and Julia Levitt

Department of Virology, Hebrew University-Hadassah Medical School, Jerusalem, Israel

Arginine is essential for the replication of herpes simplex virus. Omission of arginine from the culture medium did not affect the synthesis of viral DNA but prevented the formation of virions. Addition of arginine immediately stimulated protein synthesis which was followed by virus formation.

Received 25 May 1967; accepted 3 June 1967.





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Copyright © 1967 by the Society for General Microbiology.