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J Gen Virol 13 (1971), 95-100; DOI 10.1099/0022-1317-13-1-95
© 1971 Society for General Microbiology

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Antigenic Relationships in Avian Influenza A Viruses: Identification of Two Viruses Isolated from Turkeys in Great Britain during 1969–1970

A. P. Kendal*, C. R. Madeley{dagger} and W. H. Allan

Central Veterinary Laboratories, Weybridge, England, and Department of Clinical Virology, St Thomas's Hospital Medical School, London S.E.1

The neuraminidase (E.C. 3.2.1.18 [EC] ) of A/TURKEY/ENGLAND/69 is related antigenically to the neuraminidases of A/TURKEY/MASSACHUSETTS/65 and A/TURKEY/ENGLAND/66 avian influenza viruses, and to an A 2/1957 human influenza virus.

The neuraminidase of A/TURKEY/SCOTLAND/70 is related antigenically to the neuraminidases of A/DUTCH and virus ‘N’ (isolated before 1930 and in 1949 respectively), thus demonstrating the recurrence of a neuraminidase antigen in avian influenza A viruses over a period of at least 40 years.

The haemagglutinins of A/TURKEY/ENGLAND/69 and A/TURKEY/SCOTLAND/70 did not cross-react specifically with each other, or with viruses representing four known avian influenza A haemagglutinin prototypes.

* Present address: School of Public Health, University of Michigan, Ann Arbor, U.S.A.

{dagger} Present address: Institute of Virology, University of Glasgow, Scotland.

Received 9 December 1970; accepted 2 June 1971.





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Copyright © 1971 by the Society for General Microbiology.