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Evidence for Linkage Between Genetic Loci Controlling Response of Fowl to Subgroup A and Subgroup C Sarcoma Viruses

Houghton Poultry Research Station, Houghton, Huntingdon, England

Cells from crossbred embryos from the inbred Reaseheath R and W lines, which were segregating at the tva and tvb loci, and at a possible third locus, tvc, were examined for responses to avian sarcoma viruses of subgroups A, B and C. Responses to subgroup A were independent of those to subgroup B, as were those for subgroups B and C. Genetic analysis of the results suggested absence of linkage between the tvb locus and the tva or tvc loci.

Responses to subgroup A and C viruses were strongly associated and were consistent with linkage between the tva and tvc loci, or with the presence of a single locus which controlled responses to both subgroups.

Received 8 March 1971; accepted 9 July 1971.

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