HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Crick, J. Articles by Brown, F. Search for Related Content PubMed PubMed Citation Articles by Crick, J. Articles by Brown, F. Agricola Articles by Crick, J. Articles by Brown, F.

Interference as a Measure of Cross-relationships in the Vesicular Stomatitis Group of Rhabdo Viruses

Animal Virus Research Institute Pirbright Surrey England

The Indiana and New Jersey serotypes of vesicular stomatitis virus were differentiated by Cotton in 1927. They remained the only known members of the group until the Cocal (Jonkers et al. 1964), Brazil (Andrade et al. 1964, cited by Federer, Burrows & Brooksby, 1967) and Argentina (Garcia Pirazzi, Caggiano & Alfonso Fernandez, 1963) viruses were described. Federer et al. (1967) demonstrated a close relationship between the Cocal and Argentina strains, and although the Brazil, Argentina/Cocal and Indiana strains were shown to differ serologically, they were still considered as subtypes of a group distinct from that of the New Jersey serotype.

Cartwright & Brown (1972) confirmed recently that only the Cocal and Argentina strains showed significant cross-reactions in complement fixation and serum neutralization tests. However, the infective skeleton-like particles produced by treatment with Tween-ether or Nonidet and the infective ribonucleoprotein (RNP) released by sodium deoxycholate showed considerable cross-reactions in both tests. On this basis the major cross-reactivity was considered to be associated with the RNP.

Received 28 July 1972; accepted 29 September 1972.