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Animal Virus Research Institute, Pirbright, Woking, Surrey, England
Several of the physico-chemical properties of representative members of the Picornaviridae family have been examined. On the basis of their buoyant density in caesium chloride, stability at pH 3 to 7 and the base composition of the virus RNA, a division of this family of viruses into six subgroups is suggested.
Received 21 July 1972;
accepted 3 October 1972.
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