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Département de Microbiologie Centre Hospitalier Universitaire Université de Sherbrooke, Sherbrooke, Québec Canada
DNA-R, a replicate intermediate of adenovirus type 2 (ad. 2) DNA with a linear structure, contains a small amount of single-stranded material which can be digested by specific nucleases. The sedimentation properties of the digestion products are consistent with the assumption that DNA-R represents molecules of ad. 2 DNA replicating unidirectionally.
Received 25 September 1972;
accepted 10 April 1973.
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