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J Gen Virol 21 (1973), 425-427; DOI 10.1099/0022-1317-21-2-425
© 1973 Society for General Microbiology
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Spread of Bovine Syncytial Virus in Cell Culture

G. N. Woode and K. Smith

Agricultural Research Council Institute for Research on Animal Diseases Compton, Nr. Newbury, Berks., U.K.

The infection of MDBK cells by bovine syncytial virus did not result in the formation of syncytia. Plaques of infected cells were dispersed into single cells and quantitative studies were made on the conditions which influenced the spread of the virus. The stimulation of cell metabolism greatly enhanced the spread of virus, which was inhibited by bromodeoxyuridine.

Received 19 March 1973; accepted 27 July 1973.




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