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J Gen Virol 22 (1974), 207-214; DOI 10.1099/0022-1317-22-2-207
© 1974 Society for General Microbiology
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Neutralization of Friend Leukaemia Virus by Sera of Unimmunized Animals

M. Bendinelli, L. Nardini and M. Campa

Institute of Microbiology, University of Pisa, 56100 Pisa, Italy

The sera of several animal species neutralize Friend leukaemia virus. Among 54 serum samples taken from 16 different species only those of mouse, rat and sheep were found to be devoid of this property. The neutralizing activity is partially heat-labile and appears to require the presence of complement. Its biological significance might be considerable.

Received 31 July 1973; accepted 21 September 1973.




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Copyright © 1974 by the Society for General Microbiology.