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Institut du Radium, Université de Paris-Sud, Campus d'Orsay, France Electro-nucleonics Laboratories Inc., Bethesda, Maryland, U.S.A.
The Jackson Laboratory, Bar Harbor, Maine, U.S.A.
Mendelian analysis, combined with the use of recombinant inbred strains, has revealed the existence in the mouse of a locus with a quantitative effect on circulating interferon levels induced by mouse mammary tumour virus. This locus segregates independently from the locus that affects NDV-induced interferon levels (If-1) and has been tentatively designated as If-2.
Received 15 November 1973;
accepted 31 January 1973.
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