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Department of Experimental Virology Institute of Sera and Vaccines, Prague, Czechoslovakia
Caffeine reduced the survival of u.v.-irradiated herpes simplex type 1 virus. The relative reduction of plaque count by caffeine was most pronounced in the second component of the survival curve. With more heavily irradiated virus, when multiplicity reactivation apparently played a major role, the caffeine effect was less marked.
Received 4 March 1974;
accepted 22 April 1974.
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