J Gen Virol
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J Gen Virol 25 (1974), 453-455; DOI 10.1099/0022-1317-25-3-453
© 1974 Society for General Microbiology
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Circulating Human Interferon after Intramuscular Injection into Animals and Man

K. Cantell and Liisa Pyhälä

Department of Virology Central Public Health Laboratory, Helsinki 28 Finland

H. Strander

Radiumhemmet Karolinska sjukhuset Stockholm 60, Sweden

Intramuscular injection of concentrated human leucocyte interferon into mice, guinea pigs, rabbits, sheep and man gave a long-lasting plateau of circulating interferon. The relation between the interferon dose and the subsequent serum level was similar in all species.

Received 4 October 1973; accepted 2 November 1973.




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Copyright © 1974 by the Society for General Microbiology.