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Some Structural Antigens of Herpes Simplex Virus Type 1

D. H. Watson

Department of Virology, The Medical School, Birmingham B15 2TJ, England

Several of the major structural polypeptides of herpes simplex virus were obtained in purified form by polyacrylamide gel electrophoresis of purified virus particle polypeptides. Antisera made by footpad inoculation of these polypeptides into rabbits were used to study the antigenic properties of two envelope glycoproteins and of the major capsid protein.

^* Present address: Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas 77025, U.S.A.

Present address: Department of Microbiology, School of Medicine, Leeds LS2 9NL, England.

Received 6 May 1975; accepted 16 July 1975.