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J Gen Virol 31 (1976), 139-143; DOI 10.1099/0022-1317-31-1-139
© 1976 Society for General Microbiology

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An Improved Assay for Feline Leukaemia Virus Pseudotypes of Murine Sarcoma Virus

P. H. Russell and O. Jarrett

University of Glasgow Department of Veterinary Pathology Veterinary School, Bearsden, Glasgow G61 1QH Scotland

An assay is described for feline leukaemia virus pseudotypes of murine sarcoma virus which increased the virus titre by about 100-fold over conventional assays. The titre is independent of dilution and no secondary focus formation occurs. The assay may be used to study virus neutralization and to detect and type feline leukaemia virus in feline embryo cells by interference.

Received 22 August 1975; accepted 12 December 1975.





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