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J Gen Virol 31 (1976), 261-263; DOI 10.1099/0022-1317-31-2-261
© 1976 Society for General Microbiology
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Variants of the HR Strain of Sindbis Virus Lethal for Mice

L. R. Boone and A. Brown

Department of Microbiology, University of Tennessee, Knoxville, Tennessee 37916, U.S.A.

We have selected two similar variants of Sindbis HR virus which are lethal for mice. Consecutive brain to brain passage series were conducted in suckling and weanling mice. Specific anti-Sindbis HR neutralization tests and protection tests demonstrate that these viruses are derived from the parent Sindbis HR.

Received 8 October 1975; accepted 13 January 1976.




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Copyright © 1976 by the Society for General Microbiology.