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Department of Microbiology The Milton S. Hershey Medical Center The Pennsylvania State University College of Medicine, Hershey, Pennsylvania 17033, U.S.A.
Human cytomegalovirus (CMV) induces nuclear antigens resembling the Epstein-Barr nuclear antigen (EBNA) as early as 3 h after infection. These early antigens can be detected only with the anti-complement immunofluorescence staining (ACIF) technique. Synthesis of these new antigens is not influenced by cytosine arabinoside (ara-C).
Received 5 January 1976;
accepted 9 April 1976.
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