J Gen Virol Faster Access
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Gen Virol 33 (1976), 547-550; DOI 10.1099/0022-1317-33-3-547
© 1976 Society for General Microbiology
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Blyth, W. A.
Right arrow Articles by Harbour, D. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Blyth, W. A.
Right arrow Articles by Harbour, D. A.
Agricola
Right arrow Articles by Blyth, W. A.
Right arrow Articles by Harbour, D. A.

Reactivation of Herpes Simplex Virus Infection by Ultraviolet Light and Possible Involvement of Prostaglandins

W. A. Blyth, T. J. Hill, H. J. Field* and D. A. Harbour

Department of Bacteriology The Medical School University Walk, Bristol BS8 1TD England

Herpes simplex infection in the mouse ear was used to investigate whether various treatments would reactivate the disease. Immunosuppressive drugs failed to induce clinical signs of reactivation but irradiation of the skin of the originally infected ear with ultraviolet light or injection of prostaglandin E2 or PBSA into this site, caused reactivation of infection. This was detected by the appearance of infectious virus in the skin 2 to 3 days after these treatments. The results are discussed in relation to the mechanism of herpes reactivation in man.

* Present address: University of Cambridge, Department of Pathology, Tennis Court Road, Cambridge CB2 1QP.

Received 26 May 1976; accepted 18 August 1976.


This article has been cited by other articles:


Home page
 J. Virol.Home page
N. M. Sawtell
Quantitative Analysis of Herpes Simplex Virus Reactivation In Vivo Demonstrates that Reactivation in the Nervous System Is Not Inhibited at Early Times Postinoculation
J. Virol., April 1, 2003; 77(7): 4127 - 4138.
[Abstract] [Full Text] [PDF]

Home page
 IOVSHome page
H. E. Kaufman
Can We Prevent Recurrences of Herpes Infections without Antiviral Drugs? The Weisenfeld Lecture
Invest. Ophthalmol. Vis. Sci., May 1, 2002; 43(5): 1325 - 1329.
[Full Text] [PDF]

Home page
 J. Virol.Home page
E. Cantin, B. Tanamachi, and H. Openshaw
Role for Gamma Interferon in Control of Herpes Simplex Virus Type 1 Reactivation
J. Virol., April 1, 1999; 73(4): 3418 - 3423.
[Abstract] [Full Text]

Home page
 Am J Sports MedHome page
J. Mills, L. Hauer, A. Gottlieb, S. Dromgoole, and S. Spruance
Recurrent herpes labialis in skiers: Clinical observations and effect of sunscreen
Am. J. Sports Med., January 1, 1987; 15(1): 76 - 78.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL MICROBIOLOGY J GEN VIROL
J MED MICROBIOL ALL SGM JOURNALS
Copyright © 1976 by the Society for General Microbiology.