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Institut für Virologie and Veterinär-Pathologisches Institut, Justus Liebig-Universität, Giessen, Germany
Lectins of different specificities do not interfere with the maturation of myxoviruses; their inhibitory effect on virus replication is mainly due to prevention of the detachment of infectious virus particles from the host cell. In chick embryo fibroblasts infected with an influenza virus and treated with concanavalin A, budding occurs into intracytoplasmic vacuoles, but this phenomenon is not observed with a parainfluenza virus and with different cells.
Received 24 August 1976;
accepted 14 October 1976.
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