HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Clements, J. B. Articles by Hay, J. Search for Related Content PubMed Articles by Clements, J. B. Articles by Hay, J. Agricola Articles by Clements, J. B. Articles by Hay, J.

RNA and Protein Synthesis in Herpesvirus-Infected Cells

Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, Scotland

Introduction. Herpesviruses infect a wide range of vertebrates and are important human and animal pathogens: in a number of cases infection persists for very long periods, in a latent form, with occasional episodes of overt typical disease. In addition, several herpesviruses have been shown to be the causative agent of tumour formation in their normal hosts (e.g. Lucké frog tumour virus) or in related species (e.g. herpesvirus saimiri). Indirect evidence exists for the involvement of Epstein-Barr virus and herpes simplex virus type 2 (HSV-2) in human cancers. Thus there exist good reasons for the pursuit and identification of the mechanisms of herpesvirus infection and replication.

From the molecular virological standpoint, herpesviruses also offer an important system for study. This large virus has the potential to code for about one hundred genes and the identification of these gene products, their function and their control poses many interesting questions.

Received 13 December 1976;