HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Antignus, Y. Articles by Harpaz, I. Search for Related Content PubMed PubMed Citation Articles by Antignus, Y. Articles by Harpaz, I. Agricola Articles by Antignus, Y. Articles by Harpaz, I.

Further Studies on the Biology of an Antiviral Factor (AVF) From Virus-Infected Plants and Its Association With the N-Gene of Nicotiana Species

Virus Laboratory, The Hebrew University, Faculty of Agriculture, Rehovot, Israel

The antiviral factor (AVF) from virus-infected plants, purified on polyacrylamide gels, could be labelled with radioactive phosphorus and its activity could be eluted from the gels. The radioactivity and the antiviral activity were co-purified and thus co-electrophoresed; hence, the previously reported radioactive zone (Antignus, Sela & Harpaz, 1975) can be regarded as AVF. The production of AVF requires both the presence of the N-gene in the plant as well as virus infection. AVF production is inhibited by actinomycin D, but its activity is not affected by this drug. AVF production is correlated in time with the development of virus resistance in a local-lesion host. AVF inhibits TMV multiplication in infected leaves and suppresses virus synthesis almost totally in a local-lesion host. Some AVF is also produced when Nicotiana glutinosa L. is infected with a non-localized virus, but to a much lesser extent and at a later stage of infection. The production of AVF in N. glutinosa is not blocked at 30 °C, even though TMV is no longer localized at this temperature.

^* To whom correspondence should be addressed.

Received 29 July 1976; accepted 19 November 1976.

This article has been cited by other articles:

				M. Levy, O. Edelbaum, and I. Sela Tobacco Mosaic Virus Regulates the Expression of Its Own Resistance Gene N Plant Physiology, August 1, 2004; 135(4): 2392 - 2397. [Abstract] [Full Text] [PDF]