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Department of Entomology, London School of Hygiene and Tropical Medicine, London WC1E 7HT
Forty-six arboviruses were tested for c.p.e. and/or plaque formation in an amphibian cell line. C.p.e. was observed with a high proportion of the viruses tested. Comparative plaque assay, in the XTC-2 cells at 28 °C and Vero cells at 37 °C, suggests that these systems are comparable in sensitivity and susceptibility to infection. Practical uses of this cell line are discussed.
Received 23 September 1976;
accepted 15 December 1976.
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