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J Gen Virol 36 (1977), 323-327; DOI 10.1099/0022-1317-36-2-323
© 1977 Society for General Microbiology
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Reagents which Inhibit Disulphide Bond Formation Stabilize Human Fibroblast Interferon

T. Cartwright, O. Senussi and Madeline D. Grady

Searle Research Laboratories, Lane End Road High Wycombe Bucks. HP12 4HL, U.K.

Fibroblast interferon may be stabilized against many inactivating influences by the addition of certain simple sulphydryl reagents. The use of such easily removable and relatively non-toxic stabilizers should help in the preparation and purification of fibroblast interferon for clinical use.

Received 7 February 1977; accepted 15 March 1977.




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Copyright © 1977 by the Society for General Microbiology.