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J Gen Virol 36 (1977), 341-344; DOI 10.1099/0022-1317-36-2-341
© 1977 Society for General Microbiology

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Antiviral Activity of Bovine Interferons on Primate Cells

M. G. Tovey, Marie-Therese Bandu, Jacqueline Begon-Lours, Daniele Brouty-Boyé and I. Gresser

Institut de Recherches Scientifiques sur le Cancer, B.P. no 8 94800 Villejuif, France

Potent preparations of bovine leucocyte and fibroblast interferons had substantial antiviral activity on monkey cells and low activity on human cells. Thus, interferon from a ‘lower’ phylogenetic species can have considerable antiviral activity in primate cells, but not all primate cells are equally sensitive.

Received 21 December 1976; accepted 19 March 1977.





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