HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Michelson-Fiske, S. Articles by Febvre, H. Search for Related Content PubMed PubMed Citation Articles by Michelson-Fiske, S. Articles by Febvre, H. Agricola Articles by Michelson-Fiske, S. Articles by Febvre, H.

Growth of Cytomegalovirus at Supra-optimal Temperatures

Jacqueline Arnoult

H. Febvre

^* Collège de France, Laboratoire de Médecine Expérimentale, 11 Place Marcelin Berthelot, 75231 Paris Cedex 05
Institut National de la Santé et de la Recherche Médicale, Laboratoire de Biologie Cellulaire et de Culture de Tissus, 75005 Paris, France

An isolate (Mira) of cytomegalovirus is shown to replicate in human embryonic lung fibroblasts at supra-optimal temperature (40 °C). The ability of the Mira isolate to grow at 40 °C decreased as a function of age of cells in which the virus was grown. The unusual morphology of the lesions in late passage cells infected and maintained at 40 °C is illustrated.

Received 5 August 1976; accepted 14 April 1977.