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Studies on the Structure of a Coronavirus-Avian Infectious Bronchitis Virus

June D. Almeida

^* Virology Division, Department of Veterinary Pathology, Royal [Dick] School of Veterinary Studies, Edinburgh EH9 1QH,
Department of Virology, The Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS

When avian infectious bronchitis virus (IBV) is fixed in formaldehyde, negative stain is able to penetrate the particle and an internal component is visualized. This component is seen as a tongue or flask shaped structure attached at one point to the outer virus membrane. A model yielding transmission patterns similar to the virus has been made. Gradient centrifugation studies on IBV reveal that the RNP is associated with the internal sac.

Received 21 March 1977; accepted 22 April 1977.

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