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J Gen Virol 38 (1978), 75-82; DOI 10.1099/0022-1317-38-1-75
© 1978 Society for General Microbiology
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Proteins Induced by Infection with Caliciviruses

D. N. Black and F. Brown

Animal Virus Research Institute, Pirbright, Surrey

Three polypeptides with mol. wt. 100 (P100), 80 (P80) and 65 (P65) x 103 were found in calicivirus infected cells. P100 and P80 were present in sub-molar amounts compared with P65 and no precursor product relationship between the three polypeptides could be demonstrated using pulse-chase experiments or selective inhibitors of protein synthesis and of proteases. In the presence of protease inhibitors a polypeptide with mol. wt. 120 x 103 (P120) was demonstrated which appeared to be the precursor of P100. Possible mechanisms of translation in the caliciviruses are discussed.

Received 11 July 1977; accepted 26 July 1977.




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Copyright © 1978 by the Society for General Microbiology.