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J Gen Virol 39 (1978), 253-258; DOI 10.1099/0022-1317-39-2-253
© 1978 Society for General Microbiology
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Inhibition of African Swine Fever (ASF) Virus Replication by Phosphonoacetic Acid

M. A. Moreno, A. L. Carrascosa, J. Ortín and E. Viñuela

Centro de Biología Molecular (C.S.I.C.-U.A.M.), Velázquez 144, Madrid-6, Spain

Phosphonoacetic acid (PAA) inhibits the multiplication of African swine fever (ASF) virus in VERO cells. The observed inhibition of the in vivo DNA synthesis could be related to the in vitro inhibition of a virus-induced DNA polymerase activity present in cytoplasmic extracts from infected VERO cells.

Received 2 August 1977; accepted 21 November 1977.




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Copyright © 1978 by the Society for General Microbiology.