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J Gen Virol 39 (1978), 351-355; DOI 10.1099/0022-1317-39-2-351
© 1978 Society for General Microbiology
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A Host Range Difference between Herpes Simplex Virus types 1 and 2

Peter Goldfarb and Morag Timbury

Institutes of Genetics and Virology University of Glasgow, Church Street Glasgow, G11 5JR, U.K.

The infectivities of several strains of herpes simplex virus type 1 and type 2 were measured by plating on established human and Chinese hamster cell lines. Whereas all the type 1 strains reproducibly showed a 104-fold lower titre on the Chinese hamster cells, the type 2 strains showed only a 10- to 100-fold lower titre. This host range difference has been used in the analysis of recombinants between type 1 and type 2 viruses.

Received 11 August 1977; accepted 1 December 1977.




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Copyright © 1978 by the Society for General Microbiology.