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J Gen Virol 4 (1969), 585-591; DOI 10.1099/0022-1317-4-4-585
© 1969 Society for General Microbiology
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Amino Acid Requirement for the Propagation of Vaccinia Virus in Earle's L Cells

O. A. Holtermann

Lobund Laboratory, Notre Dame, Indiana, and Statens Seruminstitut, Copenhagen, Denmark

Using Earle's L cells, the amino acid requirement for the propagation of vaccinia virus was found to coincide with the amino acids found by Eagle (Eagle, 1955; Eagle et al. 1956) to be essential for the L cells themselves. There was no evidence that vaccinia virus particles harbour enzymes involved in amino acid synthesis.

Received 5 November 1968; accepted 16 December 1968.




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