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J Gen Virol 41 (1978), 623-628; DOI 10.1099/0022-1317-41-3-623
© 1978 Society for General Microbiology
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Ringed Plaque Formation in Infectious Pancreatic Necrosis Virus Correlates with Defective Interfering Particle Production

R. D. Macdonald

Department of Biology University of Calgary, Calgary, Alberta, Canada T2N 1N4

Four isolates of infectious pancreatic necrosis virus showed ringed plaque morphology on chinook salmon embryo cells, while six other isolates showed clear plaque morphology. One isolate chosen from the ringed-plaque class yielded defective interfering (DI) particles after as few as two virus passages starting with plaque-purified material; another isolate from the clear-plaque class failed to yield detectable numbers of DI particles.

Received 21 April 1978; accepted 12 July 1978.




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Copyright © 1978 by the Society for General Microbiology.