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J Gen Virol 42 (1979), 119-125; DOI 10.1099/0022-1317-42-1-119
© 1979 Society for General Microbiology

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Antigenicity and Polypeptide Composition of Native and Heated Echovirus Type 7 Procapsids

A. Hasegawa and S. Inouye

Central Virus Diagnostic Laboratory, National Institute of Health, 4-7-1, Gakuen, Musashimurayama, Tokyo 190-12, Japan

The native procapsid (naturally occurring empty capsid) of echovirus type 7 (E7) possesses N-antigenicity, which is as highly strain-specific as the native virion. When the native procapsid is heated, its antigenicity is converted to H-antigenicity which is common among strains of E7 and thus type-specific. However, no difference was detected in the sedimentation rate (80S) and polypeptide composition (VP0, 1 and 3) of the native and heated procapsids.

Received 26 April 1978; accepted 24 July 1978.





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Copyright © 1979 by the Society for General Microbiology.