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J Gen Virol 48 (1980), 421-424; DOI 10.1099/0022-1317-48-2-421
© 1980 Society for General Microbiology

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Cell Fusion Activity of Bovine Leukaemia Virus

M. Onuma1, S. Watarai2, T. Mikami1 and H. Izawa1

1 Department of Epizootiology Faculty of Veterinary Medicine Hokkaido University, Sapporo, Japan
2 Department of Veterinary Internal Medicine College of Dairy Agriculture, Ebetsu, Japan

Bovine leukaemia virus (BLV) induces two types of cell fusion. Cells inoculated at high multiplicity show cell fusion within 2 h. This type of fusion can be induced by non-infectious virus and does not require protein synthesis for induction. Low m.o.i. also induces cell fusion but this depends on production of infectious virus.

Received 8 November 1979; accepted 4 January 1980.





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