HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Klein, R. J. Search for Related Content PubMed PubMed Citation Articles by Klein, R. J. Agricola Articles by Klein, R. J.

Effect of Immune Serum on the Establishment of Herpes Simplex Virus Infection in Trigeminal Ganglia of Hairless Mice

Department of Microbiology New York University School of Medicine, New York, N.Y. 10016, U.S.A.

Administration of immune serum to herpes simplex virus (HSV)-infected hairless mice could not prevent acute infection in the trigeminal ganglia and the eventual establishment of latency. However, immune serum reduced the amount of free virus in the ganglion during the acute phase of the infection. It appears also that the amount of virus that can be reactivated in the latently infected ganglion is decreased. This was indicated by a prolonged reactivation time and by a reduced virus content of ganglion homogenates prepared after various periods of co-cultivation.

Received 30 January 1980; accepted 7 February 1980.

This article has been cited by other articles:

				G. N. Milligan, M. G. Meador, C.-F. Chu, C. G. Young, T. L. Martin, and N. Bourne Long-Term Presence of Virus-Specific Plasma Cells in Sensory Ganglia and Spinal Cord following Intravaginal Inoculation of Herpes Simplex Virus Type 2 J. Virol., September 1, 2005; 79(17): 11537 - 11540. [Abstract] [Full Text] [PDF]

				N. Bourne, R. B. Pyles, D. I. Bernstein, and L. R. Stanberry Modification of primary and recurrent genital herpes in guinea pigs by passive immunization J. Gen. Virol., November 1, 2002; 83(11): 2797 - 2801. [Abstract] [Full Text] [PDF]

				L. A. Morrison, L. Zhu, and L. G. Thebeau Vaccine-Induced Serum Immunoglobin Contributes to Protection from Herpes Simplex Virus Type 2 Genital Infection in the Presence of Immune T Cells J. Virol., February 1, 2001; 75(3): 1195 - 1204. [Abstract] [Full Text]

				G. N. Milligan, D. I. Bernstein, and N. Bourne T Lymphocytes Are Required for Protection of the Vaginal Mucosae and Sensory Ganglia of Immune Mice Against Reinfection with Herpes Simplex Virus Type 2 J. Immunol., June 15, 1998; 160(12): 6093 - 6100. [Abstract] [Full Text] [PDF]