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J Gen Virol 52 (1981), 313-319; DOI 10.1099/0022-1317-52-2-313
© 1981 Society for General Microbiology
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Baculovirus Replication: Stimulation of Thymidine Kinase and DNA Polymerase Activities in Spodoptera frugiperda Cells Infected with Trichoplusia ni Nuclear Polyhedrosis Virus

D. C. Kelly

Natural Environment Research Council, Institute of Virology, 5 South Parks Road, Oxford OX1 3UB, U.K.

Trichoplusia ni multiply enveloped nuclear polyhedrosis virus stimulates thymidine kinase and DNA polymerase activities in infected cells. The kinetics of induction and sensitivity of induction to cytosine arabinoside indicate that they represent early functions in infected cells. The basic characteristics of the induced enzymes are defined.

Received 16 June 1980; accepted 22 September 1980.




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