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J Gen Virol 54 (1981), 219-222; DOI 10.1099/0022-1317-54-1-219
© 1981 Society for General Microbiology
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Temperature-sensitive Mutants in Two Distinct Complementation Groups of Herpes Simplex Virus Type 1 Specify Thermolabile DNA Polymerase

Dorothy J. M. Purifoy and Kenneth L. Powell

Department of Microbiology University of Leeds, LS2 9JT, U.K.

We and others have previously shown that a mutant in herpes simplex virus type 1 (HSV-1) complementation group 1–4 induces a virus-specified DNA polymerase that is temperature-sensitive in vitro. Here we report that HSV-1 tsC7 in complementation group 1–3 also induces a thermolabile DNA polymerase.

Received 27 November 1980; accepted 19 February 1981.




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