HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Sokolov, B. P. Articles by Zhdanov, V. M. Search for Related Content PubMed PubMed Citation Articles by Sokolov, B. P. Articles by Zhdanov, V. M. Agricola Articles by Sokolov, B. P. Articles by Zhdanov, V. M.

Oligopeptide Mapping of NP Proteins of Influenza A Viruses

The D.I. Ivanovsky Institute of Virology The U.S.S.R. Academy of Medical Sciences, Gamaleya Street 16, Moscow 123098, U.S.S.R.

Oligopeptide mapping of nucleoproteins (NP proteins) of 54 strains of influenza A virus showed the presence of both common and individual oligopeptides. Using the distribution of variable oligopeptides as the criterion, NP proteins were subdivided into four groups (NP0, NP1, NP2 and NP3). The NP0 group is composed of H0N1 influenza viruses and the majority of animal influenza viruses. The NP1 group contains H1N1 (except A/California/78) and H2N2 influenza viruses isolated from man as well as H1N1 influenza viruses recently isolated from animals. A/New Jersey/76 (Hsw1N1) influenza virus also belongs to the NP1 group. The NP2 group consists of H3N2 influenza viruses isolated from man and animals. A/California/78 (H1N1) influenza virus also falls into the NP2 group. The NP3 group contains NP proteins of four animal influenza viruses with the antigenic formulas Hsw1N2, Hsw1Nav2, Hav6Nav5 and Heq2Neq2.

Keywords: oligopeptide mapping, NP proteins, influenza A virus

Received 5 May 1981; accepted 14 August 1981.