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Nucleotide Sequence of Fowl Plague Virus RNA Segment 7

Division of Virology, Department of Pathology University of Cambridge, Laboratories Block Addenbrooke's Hospital, Hills Road, Cambridge, U.K.

Nucleotide sequence analysis of a recombinant DNA clone of RNA segment 7 from FPV/Rostock/34 has shown it to be highly conserved in comparison with RNA segment 7 from two human strains (Allen et al., 1980; Winter & Fields, 1980; Lamb & Lai, 1981). FPV RNA segment 7 contains the coding capacity for two polypeptide chains. The sequence homology between RNA segment 7 of avian and human viruses was greater than 90%, and most of the changes did not result in amino acid substitutions.

Keywords: FPV, nucleotide sequence, RNA segment 7

Received 2 July 1981; accepted 7 September 1981.