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Simian Foamy Virus Pseudotypes of Vesicular Stomatitis Virus: Production and Use in Sero-epidemiological Investigations

Thomas J. Schnitzer

Imperial Cancer Research Fund Laboratories, P.O. Box 123, Lincoln's Inn Fields London WC2A 3PX, U.K.

Simian foamy virus (SFV) pseudotypes of vesicular stomatitis virus have been successfully produced and their host range characterized. The availability of these pseudotypes has permitted the development of a rapid, quantitative assay to measure neutralizing antibody titres to SFV that has proved useful in a sero-epidemiological study.

Keywords: simian foamy virus, VSV, sero-epidemiology, pseudotype

Present address: University of Michigan Medical School, Rackham Arthritis Research Unit, Ann Arbor, Michigan 48109, U.S.A.

Received 7 September 1981; accepted 2 November 1981.

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