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Production of Interferon- by Human Lymphoblastoid Cells of T and Non-T-Non-B Lineages

¹ Public Health Research Institute of Kobe City, Minatojima-naka, Chu-ou, Kobe 650, Japan
² Institute for Virus Research Kyoto University, Kyoto 606, Japan

Human lymphoblastoid cells of T and non-T-non-B lineages were examined for interferon (IFN) production induced by Sendai virus. All of the four T cell lines examined and two of the three non-T-non-B cell lines produced IFN-, and the third non-T-non-B cell line, HL-60, a mixture of IFN- and -, in contrast to two B cell lines, which produced IFN-.

Keywords: interferon, lymphoblastoid cells, Sendai virus

Received 19 November 1981; accepted 18 December 1981.