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Rackham Arthritis Research Unit University of Michigan School of Medicine Department of Epidemiology University of Michigan School of Public Health, Ann Arbor, Michigan 48109, U.S.A.
The genome of avian reoviruses is comprised of 10 segments of double-stranded (ds)RNA. Analysis by polyacrylamide gel electrophoresis of the genomic RNA from a small number of avian reoviruses has demonstrated a significant polymorphism in the migration pattern of the dsRNA segments among different isolates. Comparison of these patterns with that of the mammalian reovirus of serotype 1 has permitted calculation of the molecular weights of the avian dsRNA species.
Keywords: avian reovirus, dsRNA, genome segments, polymorphism
Received 12 November 1981;
accepted 4 March 1982.
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