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Nucleotide Sequence of the Haemagglutinin Gene of Influenza Virus A/England/321/77

Department of Microbiology, School of Medicine and School of Biological Sciences, University of Leicester, University Road, Leicester LE1 7RH, U.K.
and¹ Sandoz Forschungsinstitut Ges. m.b.H., Brunner Strasse 59, A-1235 Vienna, Austria

The complete nucleotide sequence of the haemagglutinin gene of influenza virus A/England/321/77, as determined from cloned DNA, is presented. The structure of the haemagglutinin protein encoded is compared to those of A/Victoria/75, A/Bangkok/79 and a previously published 1977 strain, A/Texas/77.

Keywords: nucleotide sequence, influenza virus, haemagglutinin, antigenic drift

Received 6 July 1982; accepted 29 July 1982.