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Virus Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT, U.K.
The buoyant density, nucleic acid, and proteins of the human serum parvovirus-like agent were investigated. Evidence is presented which suggests that the virus has genomic single-stranded DNA, and that complementary strands may be encapsidated in separate virions. Three proteins of 48000, 68000 and 80000 mol. wt. were found to co-purify with viral antigen at a density of 1.43 g/ml on CsCl gradients. On the basis of these properties it is suggested that this virus is a parvovirus.
Keywords: human parvovirus, parvovirus DNA and proteins, serum virus
Received 17 August 1983;
accepted 22 September 1983.
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