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The Role of Interferon Induction in the Interferon Sensitivity of the Mengovirus Mutant, is-1

Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, U.S.A.

An interferon-sensitive mutant of mengovirus has been shown to specifically induce interferon in infected cells. Although this appears to account for the sensitivity to interferon observed by others in an L(Y) cell line, it cannot account for the even greater sensitivity observed in our G3 line of mouse L cells.

Keywords: interferon induction, mengovirus, mouse L cells

Received 16 June 1983; accepted 14 September 1983.

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