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Synthesis of M Protein of HVJ (Sendai Virus) in Rat Glial Cells is Selectively Restricted at a Non-permissive Temperature

Department of Virology, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa 920, Japan

Production of HVJ (Sendai virus) wild-type in rat glial cells was characteristically restricted at high temperature. The synthesis of the M protein was selectively decreased in infected cells at 39°C. This temperature-sensitive (ts) character of HVJ was not observed in infection of LLCMK2 cells or chick embryo fibroblast cells. Newcastle disease virus, mumps virus and vesicular stomatitis virus did not show ts growth in glial cells.

Keywords: HVJ, Sendai virus, M protein

Received 31 August 1983; accepted 29 November 1983.