HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Boursnell, M. E. G. Articles by Brown, T. D. K. Search for Related Content PubMed PubMed Citation Articles by Boursnell, M. E. G. Articles by Brown, T. D. K. Agricola Articles by Boursnell, M. E. G. Articles by Brown, T. D. K.

Sequencing of Coronavirus IBV Genomic RNA: Three Open Reading Frames in the 5' ‘Unique’ Region of mRNA D

Houghton Poultry Research Station, Houghton, Huntingdon, Cambs. PE17 2DA, U.K.

The nucleotide sequence of a genomic cDNA clone corresponding to the 5' terminal domain of mRNA D of the Beaudette strain of infectious bronchitis virus (IBV) has been determined. This region contains three open reading frames which predict polypeptides of molecular weights 6700 (6.7K), 7.4K and 12.4K. The predicted 12.4K polypeptide has a codon usage very similar to that predicted for the products of the IBV nucleocapsid, membrane and spike genes. The sequence also predicts a hydrophobic, potentially membrane-anchoring, region in the N terminal half of the 12.4K polypeptide, and a hydrophilic C terminus.

Keywords: infectious bronchitis, coronavirus IBV, mRNA D, nucleotide sequence.

Received 23 May 1985; accepted 2 July 1985.

This article has been cited by other articles:

				A. R. Pendleton and C. E. Machamer Infectious Bronchitis Virus 3a Protein Localizes to a Novel Domain of the Smooth Endoplasmic Reticulum J. Virol., May 15, 2005; 79(10): 6142 - 6151. [Abstract] [Full Text] [PDF]

				F. Fischer, C. F. Stegen, P. S. Masters, and W. A. Samsonoff Analysis of Constructed E Gene Mutants of Mouse Hepatitis Virus Confirms a Pivotal Role for E Protein in Coronavirus Assembly J. Virol., October 1, 1998; 72(10): 7885 - 7894. [Abstract] [Full Text] [PDF]