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J Gen Virol 66 (1985), 2507-2511; DOI 10.1099/0022-1317-66-11-2507
© 1985 Society for General Microbiology

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A 28 000 Molecular Weight Human Cytomegalovirus Structural Polypeptide Studied by means of a Specific Monoclonal Antibody

Maria Carla Re, Maria Paola Landini, P. Coppolecchia, G. Furlini and M. La Placa

Institute of Microbiology of the University of Bologna, 9, Via Massarenti, I-40138 Bologna, Italy

We have produced a monoclonal antibody against human cytomegalovirus (HCMV) which recognizes a structural protein of 28 000 mol. wt. which is present in both the cytoplasm of infected cells during the late phase of the viral replication cycle and in the extracellular viral particles. This antigen was detected in all HCMV strains assayed and reacted with human sera having anti-HCMV antibodies.

Keywords: human cytomegalovirus, structural proteins, monoclonal antibody

Received 14 June 1985; accepted 2 August 1985.


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[Abstract] [Full Text] [PDF]




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