| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Medical Research Council Institute of Virology, University of Glasgow, Church Street, Glasgow G11 5JR, U.K.
The XTC-2 cell line, derived from Xenopus laevis, supported the replication of representative viruses from each of the four genera in the family Bunyaviridae. Generally, viral titres were higher in XTC-2 cells than in other susceptible cell lines, and for some viruses plaques were detected earlier in XTC-2 cells. The XTC-2 cell line permitted comparative analyses of bunyavirus-specific protein synthesis. The patterns of synthesis of viral proteins, characteristic of each of the genera, were observed with representative viruses. These studies provided biochemical characterization of two Scottish isolates, which support the inclusion of Clo Mor virus in the Nairovirus genus and St Abb's Head (M349) virus in the Uukuvirus genus.
Keywords: Bunyaviridae, XTC-2, Xenopus cell line, proteins
Present address: Virus Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, U.K.
Received 16 July 1984;
accepted 13 November 1984.
This article has been cited by other articles:
|
|
 |
|
  X. Shi, A. Kohl, P. Li, and R. M. Elliott Role of the Cytoplasmic Tail Domains of Bunyamwera Orthobunyavirus Glycoproteins Gn and Gc in Virus Assembly and Morphogenesis J. Virol., September 15, 2007; 81(18): 10151 - 10160. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. A. Altamura, A. Bertolotti-Ciarlet, J. Teigler, J. Paragas, C. S. Schmaljohn, and R. W. Doms Identification of a Novel C-Terminal Cleavage of Crimean-Congo Hemorrhagic Fever Virus PreGN That Leads to Generation of an NSM Protein J. Virol., June 15, 2007; 81(12): 6632 - 6642. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Shi, A. Kohl, V. H. J. Leonard, P. Li, A. McLees, and R. M. Elliott Requirement of the N-Terminal Region of Orthobunyavirus Nonstructural Protein NSm for Virus Assembly and Morphogenesis. J. Virol., August 1, 2006; 80(16): 8089 - 8099. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Boyd, J. K. Fazakerley, and A. Bridgen Pathogenesis of Dugbe virus infection in wild-type and interferon-deficient mice J. Gen. Virol., July 1, 2006; 87(7): 2005 - 2009. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kohl, A. C. Lowen, V. H. J. Leonard, and R. M. Elliott Genetic elements regulating packaging of the Bunyamwera orthobunyavirus genome J. Gen. Virol., January 1, 2006; 87(1): 177 - 187. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Shi, K. Brauburger, and R. M. Elliott Role of N-Linked Glycans on Bunyamwera Virus Glycoproteins in Intracellular Trafficking, Protein Folding, and Virus Infectivity J. Virol., November 1, 2005; 79(21): 13725 - 13734. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. C. Lowen and R. M. Elliott Mutational Analyses of the Nonconserved Sequences in the Bunyamwera Orthobunyavirus S Segment Untranslated Regions J. Virol., October 15, 2005; 79(20): 12861 - 12870. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. R. Novoa, G. Calderita, P. Cabezas, R. M. Elliott, and C. Risco Key Golgi Factors for Structural and Functional Maturation of Bunyamwera Virus J. Virol., September 1, 2005; 79(17): 10852 - 10863. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. C. Lowen, A. Boyd, J. K. Fazakerley, and R. M. Elliott Attenuation of Bunyavirus Replication by Rearrangement of Viral Coding and Noncoding Sequences J. Virol., June 1, 2005; 79(11): 6940 - 6946. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kohl, E. F. Dunn, A. C. Lowen, and R. M. Elliott Complementarity, sequence and structural elements within the 3' and 5' non-coding regions of the Bunyamwera orthobunyavirus S segment determine promoter strength J. Gen. Virol., November 1, 2004; 85(11): 3269 - 3278. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
X. Shi, D. F. Lappin, and R. M. Elliott Mapping the Golgi Targeting and Retention Signal of Bunyamwera Virus Glycoproteins J. Virol., October 1, 2004; 78(19): 10793 - 10802. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Thomas, G. Blakqori, V. Wagner, M. Banholzer, N. Kessler, R. M. Elliott, O. Haller, and F. Weber Inhibition of RNA Polymerase II Phosphorylation by a Viral Interferon Antagonist J. Biol. Chem., July 23, 2004; 279(30): 31471 - 31477. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kohl, T. J. Hart, C. Noonan, E. Royall, L. O. Roberts, and R. M. Elliott A Bunyamwera Virus Minireplicon System in Mosquito Cells J. Virol., June 1, 2004; 78(11): 5679 - 5685. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kohl, R. F. Clayton, F. Weber, A. Bridgen, R. E. Randall, and R. M. Elliott Bunyamwera Virus Nonstructural Protein NSs Counteracts Interferon Regulatory Factor 3-Mediated Induction of Early Cell Death J. Virol., July 15, 2003; 77(14): 7999 - 8008. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Streitenfeld, A. Boyd, J. K. Fazakerley, A. Bridgen, R. M. Elliott, and F. Weber Activation of PKR by Bunyamwera Virus Is Independent of the Viral Interferon Antagonist NSs J. Virol., May 1, 2003; 77(9): 5507 - 5511. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. J. Salanueva, R. R. Novoa, P. Cabezas, C. Lopez-Iglesias, J. L. Carrascosa, R. M. Elliott, and C. Risco Polymorphism and Structural Maturation of Bunyamwera Virus in Golgi and Post-Golgi Compartments J. Virol., December 20, 2002; 77(2): 1368 - 1381. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. Krauss, R. Hollinshead, M. Hollinshead, and G. L. Smith An investigation of incorporation of cellular antigens into vaccinia virus particles J. Gen. Virol., October 1, 2002; 83(10): 2347 - 2359. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Weber, A. Bridgen, J. K. Fazakerley, H. Streitenfeld, N. Kessler, R. E. Randall, and R. M. Elliott Bunyamwera Bunyavirus Nonstructural Protein NSs Counteracts the Induction of Alpha/Beta Interferon J. Virol., July 17, 2002; 76(16): 7949 - 7955. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. J. Sanchez, M. J. Vincent, and S. T. Nichol Characterization of the Glycoproteins of Crimean-Congo Hemorrhagic Fever Virus J. Virol., June 14, 2002; 76(14): 7263 - 7275. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Kochs, C. Janzen, H. Hohenberg, and O. Haller Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexes PNAS, March 5, 2002; 99(5): 3153 - 3158. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Bridgen, F. Weber, J. K. Fazakerley, and R. M. Elliott Bunyamwera bunyavirus nonstructural protein NSs is a nonessential gene product that contributes to viral pathogenesis PNAS, January 16, 2001; 98(2): 664 - 669. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Bridgen and R. M. Elliott Rescue of a segmented negative-strand RNA virus entirely from cloned complementary DNAs PNAS, December 24, 1996; 93(26): 15400 - 15404. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| INT J SYST EVOL MICROBIOL | MICROBIOLOGY | J GEN VIROL |
| J MED MICROBIOL | ALL SGM JOURNALS | |
