HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Farrar, G. H. Articles by Greenaway, P. J. Search for Related Content PubMed PubMed Citation Articles by Farrar, G. H. Articles by Greenaway, P. J. Agricola Articles by Farrar, G. H. Articles by Greenaway, P. J.

Characterization of Glycoprotein Complexes Present in Human Cytomegalovirus Envelopes

Molecular Genetics Laboratory, Centre for Applied Microbiology and Research, PHLS, Porton Down, Salisbury SP4 0JG, U.K.

Three disulphide cross-bridged glycoprotein complexes were immunoprecipitated from purified human cytomegalovirus envelopes using a monoclonal antibody with a specificity for a glycoprotein of mol. wt. 52 x 10³. These complexes were isolated by electroelution after polyacrylamide gel electrophoresis (PAGE) under non-reducing conditions. Compositional analysis of each complex by PAGE under reducing conditions showed that at least two distinct complexes,one containing glycoproteins with mol. wt. of 52 x 10³ and 95 x 10³ and the other with glycoproteins of 52 x 10³ and 130 x 10³, were present. The results obtained indicated that one of these complexes could also exist as a dimer.

Keywords: HCMV, envelope, glycoprotein complexes

Received 7 January 1986; accepted 14 March 1986.

This article has been cited by other articles:

				K. A. Boyle, R. L. Pietropaolo, and T. Compton Engagement of the Cellular Receptor for Glycoprotein B of Human Cytomegalovirus Activates the Interferon-Responsive Pathway Mol. Cell. Biol., May 1, 1999; 19(5): 3607 - 3613. [Abstract] [Full Text] [PDF]