HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Diallo, A. Articles by Taylor, W. P. Search for Related Content PubMed PubMed Citation Articles by Diallo, A. Articles by Taylor, W. P. Agricola Articles by Diallo, A. Articles by Taylor, W. P.

Comparison of Proteins Induced in Cells Infected with Rinderpest and Peste des Petits Ruminants Viruses

¹ Institute for Animal Disease Research, Pirbright Laboratory, Ash Road, Pirbright, Woking GU24 0NF, U.K.
² Institut d'Elevage et de Médicine Vétérinaire des Pays Tropicaux, 10 rue Pierre-Curie, 94700 Maisons-Alfort, Paris, France
and³ Food and Agricultural Organization, P.O. Box 30570, Nairobi, Kenya

The two morbilliviruses rinderpest virus (RPV) and peste des petits ruminants virus (PPRV) are closely related and cause severe disease in large and small ruminants, respectively. They show distinct epidemiological patterns and are distinguishable by reciprocal cross-neutralization tests. We have analysed the proteins induced by these viruses in infected cells and have shown that they can be distinguished by a very marked difference in the apparent mol. wt. of the nucleocapsid (N) protein. The N protein of PPRV is almost identical in mobility on polyacrylamide gels to the N proteins of measles virus and canine distemper virus (60K). Several strains of RPV and PPRV from widespread geographical locations were studied and found to show this difference in the N protein.

Keywords: rinderpest, peste des petits ruminants, morbillivirus proteins

Received 4 February 1987; accepted 2 April 1987.

This article has been cited by other articles:

				E. P. Walsh, M. D. Baron, L. F. Rennie, P. Monaghan, J. Anderson, and T. Barrett Recombinant Rinderpest Vaccines Expressing Membrane-Anchored Proteins as Genetic Markers: Evidence of Exclusion of Marker Protein from the Virus Envelope J. Virol., November 1, 2000; 74(21): 10165 - 10175. [Abstract] [Full Text]

				E. P. Walsh, M. D. Baron, J. Anderson, and T. Barrett Development of a genetically marked recombinant rinderpest vaccine expressing green fluorescent protein J. Gen. Virol., March 1, 2000; 81(3): 709 - 718. [Abstract] [Full Text]