HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Ignjatovic, J. Search for Related Content PubMed PubMed Citation Articles by Ignjatovic, J. Agricola Articles by Ignjatovic, J.

Isolation of a Variant Endogenous Avian Leukosis Virus: Non-productive Exogenous Infection with Endogenous Viruses Containing p27 and p27°

CSIRO Division of Animal Health, Animal Health Research Laboratory, Private Bag No. 1, P.O., Parkville, Victoria 3052, Australia

Ten replication-competent endogenous avian leukosis viruses (ALVs) with subgroup E specificity were isolated from six commercial chicken lines of mixed breed. All the ALVs isolated belonged to a variant class of endogenous viruses with a major group-specific antigen, p27, identical in size to that of exogenous viruses and different from the p27° of endogenous viruses isolated from White Leghorn chickens. It was possible to infect chickens exogenously with endogenous viruses (containing p27) and with Rous-associated virus type 0 (containing p27°) but infection was non-productive. Congenital transmission and shedding did not occur in chickens infected with endogenous viruses containing p27° or in chickens infected with endogenous viruses containing p27. Restriction of endogenous virus replication in some tissues (heart, spleen and meconia) of viraemic chickens was observed suggesting that exogenous infection of chickens with endogenous viruses differs from an infection with exogenous ALVs.

Keywords: ALV, endogenous, transmission, congenital, variants

Received 15 June 1987; accepted 30 October 1987.