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J Gen Virol 69 (1988), 1601-1608; DOI 10.1099/0022-1317-69-7-1601
© 1988 Society for General Microbiology

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The Immunological Relationship between Canine Herpesvirus and Four Other Herpesviruses

A. Manning, A. Buchan, G. R. B. Skinner, J. Durham and H. Thompson1

Department of Medical Microbiology, The Medical School, University of Birmingham, Birmingham B15 2TJ
and1 Department of Veterinary Pathology, University of Glasgow, Veterinary School, Bearsden Road, Bearsden, Glasgow G61 1QH, U.K.

Canine herpesvirus (CHV) was compared with four other herpesviruses by several serological techniques. Cross-neutralization was demonstrated between CHV and herpes simplex virus types 1 and 2 and pseudorabies virus. Non-neutralizing cross-reactions were found with these viruses and also with equine abortion virus and bovine mammillitis virus. The data suggest that CHV is immunologically more closely related to herpes simplex virus than to the other viruses used in this study.

Keywords: CHV, herpesviruses, cross-reactivity

Received 30 December 1987; accepted 10 March 1988.





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